5月6日:Poly(dopamine) and its derivatives for adhesives and coatings

  报告题目:Poly(dopamine) and its derivatives for adhesives and coatings 

  报 告 人:Haeshin Lee,Korea Advanced Institute of Science & Technology 

  报告时间:56(星期五) 下午1500 

  报告地点:理化楼三楼多功能厅 

  报告人简介: 

 

 
 http://sticky.kaist.ac.kr 

  Haeshin Lee, Ph.D. (Last update: April, 2016) 

  Associate Professor, 

  Department of Chemistry, KAIST Institute NanoCentury Korea Advanced Institute of Science & Technology (KAIST) 

  Phone: 042-350-2849 haeshin@kaist.ac.kr http://sticky.kaist. ac.kr 

  Education 

  Ph.D. Biomedical Engineering, Northwestern University, June 2008 (Advisor Phillip B. Messersmith) 

  B.S. Biological Sciences, Korea Advanced Institute of Science & Technology (KAIST), Mar. 1993 - Feb. 1997. 

  Research and Academic Career 

  Korea Adhesive and Interface Society, Academic Board Members (2015 ~) Bio-Therapeutic Delivery Society, Academic Board Members (2015 ~) 

  Post-doc Fellow, Department of Chemical Engineering, MIT (Advisor Robert S. Langer & Daniel G. Anderson), 2008 

  Researcher, Department of Biochemistry and Molecular Biology, The University of Chicago, Feb. 2002 - Aug. 2003 

  Researcher, Department of Biological Sciences, Korea Advanced Institute of Science & Technology May 2000 - Jan. 2002; Oct. 1997 - Apr. 1998 Research Assistant, Department of Biological Science, Gwang-Ju Institute Science & Technology (GIST), March 1997 - Nov. 1997 

  Book Chapter 

  Kyuri Kim, Seonki Hong, Haeshin Lee 'Mussel-inspired adhesive biomaterials' Ch12 Vol 1, in Handbook of Biomimetics and Bioinspiration. pp 273-291 (http://dx.doi.org/10.1142/9789814354936 0012) 2014. 

  Haeshin Lee, Phillip B. Messersmith, 'Bio-inspired nano-materials for a new generation of medicine' Edited by Tuan Vo-Dinh in Nanotechnology in Biology and Medicine, Chapter 3, CRC Press, ISBN 0849329493, 2007 (Jan, 24th) 

  Awards and Honors 

  1.  KAIST Excellence in Research (^^^^^) (2015), KAIST Collaborative Award (^ 2013^.), KAIST Pioneering New Knowledge Award                                                2012\1), KAIST Excellence in Teaching (2010, 2011, and 2014) 

  2.  POSCO Chung-Am Award (^# ^##) (2011^) 

  3.  Top 100 Science Stories Discover Magazine, 2008, January 

  4.  NASA Inventor Award (2008^) 

  5.  The Future-leading Scientist Award (^^^^^^) 2007, The Ministry of Science and Education (^^7#^) 

  6.  Graduate Student Award, Materials Research Society Meeting, Boston, 2007 

  7.  Richard W. Jones best poster award, 2007, BME, Northwestern University 

  Publications (Current citations: ~ 9,900 times, H-index = 40) 

  1.  Mihyun Lee, S. H. Lee, I-K. Oh, Haeshin Lee, "Microwave-accelerated rapid, chemical oxidant-free, material-independent surface chemistry of poly(dopamine)" Small 2016, accepted 

  2.   S. Ma. Haeshin Lee, Y Liang, Feng Zhou* 'Astringent mouthfeel as a consequence of lubrication failure' Angew. Chemie. Int. Ed. 2016, 55, online (http://dx.doi.org/10.1002/anie.201601667) 

  3.   Mikyung Shin, K. Kim, W. Shim, J. W. Yang, Haeshin Lee "Tannic acid as a degradable mucoadhesive compound" ACS Biomaterials Sci & Eng. 2016, 2, 687-696 (http://dx.doi.org/10.1021/acsbiomaterials.6b00051) 

  4.   Sang Hyeon Hong, S. Hong, M.-H. Ryou, J. W. Choi, Sung Min Kang*, Haeshin Lee* "Sprayable ultrafast surface modification" Adv. Mater. Interfaces 2016, online (http://dx.doi.org/10.1002/admi.201500857) 

  5.   M. Kim, J.-S. Kim, Haeshin Lee, Jae-Hyung Jang* "Polydopamine-decorated sticky, water- friendly, biodegradable polycarprolactone cell carriers" Macromol. Biosci. 2016 online (http://dx.doi.org/10.1002/mabi.201500432) 

  6.   Sang Hyeon Hong, M. Shin, J. Lee, J. H. Ryu, S. Lee, J. W. Yang, W. D. Kim, Haeshin Lee, "STAPLE: stable alginate gel prepared by linkage exchange from ionic to covalent bonds" Adv. Healthcare Mater. 2016, 5, 75-79 (http://dx.doi.org/10.1002/adhm.201400833) 

  7.   Mihyun Lee, Y. Kim, J. H. Ryu, K. Kim, Y.-M. Han*, Haeshin Lee* "Long-term, feeder-free maintenance of human embryonic stem cells by mussel-inspired adhesive heparin and collagen Type I" Acta Biomaterialia 2016, 32, 138-148 (online Jan 23th, 2016), http://dx.doi.org/10.1016/j.actbio.2016.01.008 

  8.   Chanoong Lim, J. Huang, Sunjin Kim, H. Zeng*, Haeshin Lee*, D. S. Hwang* "Nanomechanics of poly(catecholamine) coatings in aqueous solutions" Angew. Chemie. Int. Ed. 2016, 55, 3342-46 http://dx.doi.org/10.1002/anie.201510319 

  9.   Hui-Lian Che, I.-H. Bae, K. S. Lim, S. Uthaman, In Taek Song, Haeshin Lee, D. Lee, W. J. Kim, Y. Ahn, In-Kyu Park, M.-H. Jeong "Novel fabrication of microRNA nanoparticles-coate coronary stent for prevention of angioplasty restenosis" Korean Circulation J. 2016, 46, 23-32 http://dx.doi.org/10.4070/kci.2016.46.L23 

  10.  H. Joo, Eunkyoung Byun, M. Lee, Y. Hong, Haeshin Lee*, Pilnam Kim*, "Biofunctionalization via flow shear stress resistant adhesive polysaccharide, hyaluronic acid- catechol for enhanced in vitro endothelialization" J. Industrial & Eng. Chem. 2016, 34, 14-20 http://dx.doi.org/10.1016/j.jiec.2015.11.015 

  11.  Kyueui Lee, E. Prajatelistia, D. S. Hwang, Haeshin Lee* "Role of dopamine chemistry in the formation of mechanically strong mandibles of Grasshoppers" Chem. Mater. 2015, 27, 6478 (pub. date: July 27 th)   http://dx.doi.org/10.1021/acs.chemmater.5b01680 

  12.  Ji Hyun Ryu, Seonki Hong, Haeshin Lee, "Bio-inspired adhesive catechol-conjugated chitosan for biomedical applications: A mini review" Acta Biomaterialia 2015, 27, 101-115. 

  13.  Seongwoo Ryu, Byung Gon Kim, Jang Wook Choi, Haeshin Lee "Highly oriented carbon nanotube sheets for rechargeable lithium oxygen battery electrodes" J. Nanosci. Nanotech. 2015, 15, 7611-7614 

  14.  Shazid Md. Sharker, S. M. Kim, J. E. Lee, K. H. Choi, G. Shin, S. Lee, K. D. Lee, J. H. Jeong, Haeshin Lee*, Sung Young Park "Functionalized biocompatible WO3 nanoparticles for triggered and targeted in vitro and in vivo photothermal therapy" J. Control. Rel 2015, 217, 211-220. 

  15. Hui-Lian Che, In-Ho Bae, K. S. Lim, In Taek Song, Haeshin Lee, D. Lee, W. J. Kim, M.-H. Jeong, In-Kyu Park*, Y. Ahn* "Therapeutic effect of Akt1 siRNA nanoparticle eluting stent on the suppression of post-angioplasty restenosis, J. Biomed. Nanotech.". 2015, accepted. 

  16. Jisoo Shin, J. S. Lee, C. Lee, H.-J. Park, K. Yang, Y. Jin, Ji Hyun Ryu, K. S. Hong, S.-H. Moon, H.-M. Chung, H. S. Yang, S. H. Um, J.-W. Oh, D.-I. Kim, Haeshin Lee, Seung-Woo Cho "Tissue adhesive catechol-modified hyaluronic acid hydrogel for effective, minimally invasive cell therapy" Adv. Funct. Mater. 2015, 25, 3814-24 

  17.  Shazid Md. Sharker, Sung Min Kim, Sung Han Kim, Insik In, Haeshin Lee*, Sung Young Park* "Target delivery of beta-cyclodextrin/paclitaxel complexed fluorescent carbon nanoparticles: externally NIR light and internally pH sensitive-mediated release of paclitaxel with bio-imaging" J. Mater. Chem. B. 2015, 3, 5833-41 (DOI: 10.1039/CTB00779H) 

  18.  Joseph P. Park, M.-Y. Koh, P. S. Sung, K. Kim, M. S. Kim, M. S. Lee, E.-C. Shin, K. H. Kim, Haeshin Lee "Inactivation efficiency of DNA and RNA viruses during chitin-to-chitosan conversion" Macromol. Res. 2015, 23, 505-8 

  19.  J. S. Lee, K. Kim, K. Kim, J. P. Park, K. Yang, S.-W. Cho*, Haeshin Lee* "Surface chemistry of vitamin: Pyridoxal 5'-phosphate (Vitamin B6) as a multifunctional compound for surface functionalization" Adv. Funct. Mater. 2015, 25, 4754-60 (Inside Cover Article) 

  20.  G. Jin, M. Shin, S.-H. Kim, Haeshin Lee*, J.-H. Jang* "SpONGE: Spontaneous organization of numerous-layer generation by electrospray" Agnew. Chemie. Int. Ed. 2015, 54, 7587-7591 (June 22, 2015) (DOI: 10.1002/anie.201502177) 

  21.  H. Y. Lee, H. Jeong, B. Jang, Y. C. Seo, Haeshin Lee, Hyukjin Lee, "DhiTACT: DNA hydrogel formation by IsoThermal Amplification of Complementary Target in Fluidic Channels" Adv. Mater. 2015, 27, 3531-3517 (Inside cover) 

  22.  S. Ryu, J. B. Chou, K. Lee, D. Lee, S. H. Hong, R. Zhao, Haeshin Lee,* Sang-gook Kim* "Direct insulation-to-conduction transformation of adhesive catecholamine for simultaneous increases of electrical conductivity and mechanical strength of CNT fibers" Adv. Mater. 2015, 27, 3250-3255 (Cover article) 

  23.  Shazid Md. Sharker, J. E. Lee, S. H. Kim, J. H. Jeong, I. In, Haeshin Lee,* S. Y. Park* "pH triggered in vivo photothermal therapy and fluorescence nanoplatform of cancer based on responsive polymer-indocyanine green integrated reduced graphene oxide" Biomaterials 2015, 61, 229-238 

  24.  Shazid Md. Sharker, S. M. Kim, J.-E. Lee, J. H. Jeong, I. In, K. D. Lee, Haeshin Lee*, S. Y. Park* "In situ synthesis of luminescent carbon nanoparticles toward target bioimaging" Nanoscale 2015, 7, 5468-75. (DOI: 10.1039/C4NR07422J) 

  25.  Keumyeon Kim M. Shin, M-Y Koh, J. H. Ryu, M. S. Lee, S. Hong*, Haeshin Lee* "TAPE: a medical adhesive inspired by a ubiquitous compound in plants" Adv. Funct. Mater. 2015 25, 2402-2410 (March 16) 

  26. K. Kim, K. Kim, J. H. Ryu, Haeshin Lee "Chitosan-Catechol: A Polymer with Long-lasting Mucoadhesive Properties" Biomaterials 2015, 52, 161-170 

  27. Mikyung Shin, J. H. Ryu, J. P. Park, K. Kim, J. W. Yang, Haeshin Lee "DNA/Tannic acid hybrid gel exhibiting biodegradability, extensibility, tissue adhesiveness, and hemostatic ability" Adv. Funct. Mater. 2015, 25, 1270-78 (Feb, 25). 

  28. H.-J. Park, K. Yang, M.-J. Kim, J. Jang, Mihyun Lee, D.-W. Kim, Haeshin Lee*, S.-W. Cho* "Bio-inspired oligovitronectin-grafted surface for enhanced self-renewal and long-term maintenance of human pluripotent stem cells under feeder-free conditions" Biomaterials 2015, 50, 127-139 

  29.  S. M. Kang, Haeshin Lee "One-step immobilization of initiators for surface-initiated ROP and ATRP by poly (norepinephrine) coating" J. Nanosci. Nanotech. 2015, 15, 1597-1600. 

  30.  Joseph Park, In Taek Song, J. Lee, Ji Hyun Ryu, Y. Lee, Haeshin Lee "Vanadyl-Catecholamine Hydrogels Inspired by Ascidians and Mussels" Chem. Mater. 2015, 27, 105-111. 

  31.  J. M. Lee, Ji Hyun Ryu, E. A. Kim, S. Jo, B.-S. Kim, Haeshin Lee*, Gun-Il Im*, "Adhesive barrier/directional controlled release for cartilage repair by endogeneous progenitor cell recruitment" Biomaterials 2015, 39, 173-181. 

  32.  Mihyun Lee, K. Yang, Y. H. Hwang, Y. Byun, D. Y. Lee, S.-W. Cho, Haeshin Lee "Spheroform: Therapeutic spheroid-forming nanotextured surface inspired by desert beetle, Physosterna cribripes" Adv. Healthcare Mater. 2015, 4, 511-515 (pub Oct 17, 2014) (DOI: 10.1002/adhm.201400429) 

  33.  Ji Hyun Ryu, S. Jo, Mi-Young Koh, and Haeshin Lee, "Bio-inspired, Water-soluble to insoluble self-transition for flexible, biocompatible, transparent, catecholamine polysaccharide thin film" Adv. Funct. Mater. 2014, 24, 7709-16 (DOI: 10.1002/adfm.201402250) (Oct 6, 2014) 

  34.  Joseph Park, M. Do, H.-E. Jin, Seung-Wuk Lee, Haeshin Lee "M13 bacteriophage displaying DOPA on surfaces: fabrication of various nanostructured inorganic materials without time-consuming screening processes" ACS Appl. Mater. & Interf. 2014, 6, 18653-18660 (DOI: 10.1021/am506873g) (Oct. 15) 

  35.  S. Ryu, K. Lee, S. H. Hong, Haeshin Lee, "Facile method to sort graphene quantum dot by size through ammonium sulfate addition" RSCAdvances, 2014, 4, 56848-52 

  36.  S. Ryu. Y. Kim, Haeshin Lee*, S. H. Hong* "Dry Spun 3D Woven Carbon Nanotube Anode Electrode for Li-Ion Batteries" J. Nanotech. Nanosci. 2014, 14, 9152-57 

  37.  Insung You, Tae Geol Lee, Y. S. Nam, Haeshin Lee "Fabrication of micro-omnifluidic device by omniphilic/omniphobic patterning on nanostructured surfaces" ACS Nano, 2014, 8, 9016-9024 

  38.  E. H. Jeong, Ji Hyun Ryu, H. S. Jung, B. Jang, H. Y. Lee, S. Hong, Haeshin Lee, Hyukjin Lee, "Efficient Delivery of siRNAs by Photothermal Approach using Plant Flavonoid-inspired Gold Nanoshells" Chem. Comm. 2014, 50, 13388-13390 (DOI: 10.1039/C4CC07155G) 

  39.  Seonki Hong, C. F. Schaber, K. Dening, E. Appel, Stanislav N. Gorb, Haeshin Lee* "Air/Water Interfacial formation of free-standing, stimuli-responsive, self-healing catecholamine Janus- faced microfilm" Adv. Mater. 2014 26, 7581-87 (Inside Front Cover) 

  40.  C. Yang, X. Ding, R. J. Ono, Haeshin Lee, L. Y. Hsu, J. Hedrick, Yi Yan Yang, "Bruch-like polycarbonates containing dopamine, cation, and PEG, providing a broad spectrum, antibacterial, and antifouling surface via one-step coating" Adv. Mater. 2014, 26, 7346-51 (DOI: 10.1002/adma.201402059). 

  41.  B. G. Kim, S. Kim, Haeshin Lee*, J. W. Choi "Wisdom from human eye: A synthetic melanin radical scavenger for improved cycle life of LiO2 battery" Chem. Mater. 2014, 26, 4757-4764. 

  42.  Shazid Md. Sharker, C. J. Jeong, S. M. Kim, J.-E. Lee, J. H. Jeong, Insik In, Haeshin Lee*, S. Y.Park* "Photo- and pH-tunable multicolor fluorescent nanoparticle-based spiropyran- and BODIPY-conjugated polymer with graphene oxide" Chem. Asian J. 2014 9, 2921-2927 (July 23th). 

  43.  Seonki Hong, Hyukjin Lee, Haeshin Lee* "Controlling mechanical properties of bio-inspired hydrogels by modulating nano-scale, inter-polymeric junctions" Beilstein J. Nanotech. 2014, 5, 887-894. 

  44.  E. Kim, S. Lee, S. Hong, G. Jin, M. Kim, K. I. Park, Haeshin Lee*, Jae-Hyung Jang* "Sticky 'delivering-from' strategies using viral vectors for efficient hyman neural stem cell infection by bioinspired catecholamines" ACS. Appl. Mater. & Interfaces 2014, 6, 8288-94 (June 11) 

  45.  S. Hong, J. Yeom, I. T. Song, S. M. Kang, Hyukjin Lee, Haeshin Lee "Pyrogallol 2- aminoethane: a plant flavonoid-inspired molecule for material-independent surface chemistry" Adv. Mater. Interfaces 2014, 1, 1400113 (DOI: 10.1002/admi.201400113) 

  46.  J. Y. Ryu, I. T. Song, A. K. H. Lau, P. B. Messersmith, T.-Y.Yoon, Haeshin Lee "New anti-fouling platform characterized by single-molecule imaging" ACS Appl. Mater. Interfaces 2014, 6, 3553-58 (DOI: 10.1021/am4057387) (Feb 14). 

  47.  E. Byun, Haeshin Lee "Enhanced loading efficiency and sustained release of doxorubicin from hyaluronic acid/graphene oxide composite hydrogels by a mussel-inspired catecholamine" J. Nanosci. Nanotech. 2014, 14, 7395-7401 

  48.  M. S. Lee, J. E. Lee, E. Byun, N. W. Kim, K. Lee, Haeshin Lee, S. J. Sim, D. S. Lee, J. H. Jeong "Target-specific delivery of siRNA by stabilized calcium phosphate nanoparticles using dopa-hyaluronic acid conjugate" J. ControlledRel. 2014, 192, 122-130 

  49.  I. You, Y. C. Seo, Haeshin Lee "Material-independent fabrication of superhydrophobic surfaces by mussel-inspired polydopamine" RSC Advances, 2014, 4, 10330-3. 

  50.  N. W. Kim, M. S. Lee, K. R. Kim, J. E. Lee, K. Lee, J. S. Park, Y. Matsumoto, D. G. Jo, Haeshin Lee, D. S. Lee, J. H. Jeong "Polyplex-releasing microneedles for enhanced cutaneous delivery of DNA vaccine" J. Controlled Rel. 2014, 179, 11-17 (online pub. Jan 23) 

  51.  E. Byun, J. H. Ryu, Haeshin Lee "Catalyst-mediated yet catalyst-free hydrogels formed by interfacial chemical activation" Chem. Comm. 2014, 50, 2869 (DOI: 10.1039/C3CC49043B) (publication date: Jan 20, 2014) 

  52.  M. Park, M. Shin, E. Kim, S. Lee, K. I. Park, Haeshin Lee*, Jae-Hyung Jang* "The promotion of human neural stem cells adhesion using bio-inspired poly(norepinephrine) nanoscale coating" J. Nanomaterials 2014, 793052, p10 (http://dx.doi.org/10.1155/2014/793052) 

  53.  Mikyung Shin, Hong Kee Kim, Haeshin Lee "Dopamine-loaded PLGA microspheres: new strategy of encapsulating small hydrophilic drugs with high efficiency" Biotechnol. Prog. 2014, 30, 215-23 (Nov. 23, 2013) (DOI: 10.1002/btpr.1835). 

  54.  Joseph Park, M.-J. Choi, S. H. Kim, Seung Hwan Lee, Haeshin Lee* "Preparation of sticky Escherichia coli through surface display of adhesive catecholamine moiety" Applied and Environ. Microbiol. 2014, 80 (1), 43-53. (http://dx.doi.org/10.1128/AEM.02223-13) (Pub: Oct 11) 

  55.  Ji Hyun Ryu, Y. Lee, M. J. Do, S. D. Jo, J. S. Kim, B.-S. Kim, G.-I. Im, T. G. Park, Haeshin Lee "Chitosan-g-hematin: Enzyme-mimicking Polymeric Catalyst for Adhesive Hydrogels" Acta Biomaterialia 2014, 10, 224-233 (Pub: Sep, 24) (http://dx.doi.org/10.1016/j.actbio.2013.09.014) 

  56.  M.-H. Ryou, S. Hong, M. Winter, Haeshin Lee*, Jang Wook Choi* "Improved cycle lives of LiMn2O4 cathodes in lithium ion batteries by an alginate biopolymer from seaweed" J. Mater. Chem. A 2013, 1, 15224-15229 (DOI: 10.1039/C3TA13514D) (Pub: Oct 8) (Dec, 28 issue) 

  57.  S. Ryu, C. B. Mo, Haeshin Lee, Soon Hyung Hong "Fabrication process and electromagnetic wave absorption characterization of a CNT/Ni/epoxy nanocomposite" J. Nanosci. Nanotech. 2013, 13, 7669-74 

  58.  J. Lee, S. H. Yang, S.-P. Hong, D. Hong, Haeshin Lee, H.-Y. Lee, Y.-G. Kim, I. S. Choi "Chemical control of yeast cell division by cross-linked shells of catechol-grafted polyelectrolyte multilayers" Macromol. Rapid Comm. 2013, 34, 1351-6 

  59. A. Nahan, Lee, J.-E. Lee, Insik In, Haeshin Lee, K.-D. Lee, Ji Hoon Jeong, Sung Young Park. "Target Delivery and Cell Imaging Using Hyaluronic Acid Functionalized Graphene Quantum Dot" Mol. Pharmaceutics 2013 10, 3736-44. 

  60.  D. Hong, I. You, Haeshin Lee, S.-G. Lee, I. S. Choi, S. M. Kang "Polydopamine circle-patterns on a superhydrophobic AAO surface: water-capturing property" Bull. Korean Chem. Soc. 2013, 34, 3141-42 

  61.  J. Y. Park, J. Yeom, J. S. Kim, M. Lee, Haeshin Lee*, Y. S. Nam* "Cell-repellent Dextran Coatings of Porous Titania using Mussel Adhesion Chemistry" Macromol. Biosci. 2013, 13, 1511-19 (DOI: 10.1002/macp.20) (July 31) (Nov. 13) 

  62.  S. Hong, J. Kim, Y. S. Na, J. Park, S. Kim, K. Singha, G.-I. Im, W. J. Kim, Haeshin Lee, "Poly(norepinephrine): Ultra-smooth, Material-independent Surface Chemistry and Nano-depot for Nitric Oxide" Angew. Chemie. Int. Ed. 2013, 52, 9187-9191 (Aug, 26) 

  63.  M.-J. Do, Kyuri Kim, Haeshin Lee, Seho Cha, Taegun Seo, Hee-Jung Park, Jeong-Soon Lee, Tae-Il Kim "Development of animal experimental periodontitis models" J. Periodontal Implant Sci. 2013, 43, 147-152. 

  64.  S. Ryu, B. Lee, S. Hong, S. Jin, S. Park, S. H. Hong, Haeshin Lee, "Salting-out as a scalable, in-series purification method of graphene oxides from microsheets to quantum dots" Carbon, 2013, 63, 45-53 (DOI: 10.1016/j.carbon.2013.06.037). 

  65.  H. Y. Son, J. H. Ryu, Haeshin Lee, Y. S. Nam "Bio-inspired Templating Synthesis of Metal- Polymer Hybrid Nanostructures within 3D Electrospun Fibers" ACS Appl. Mater. Interfaces 2013, 5, 6381-90 

  66.  S. Jo, S. M. Kang, S. A. Park, W. D. Kim, Haeshin Lee "Enhanced adhesion of pre-osteoblast inside 3D PCL scaffolds by polydopamine coating and mineralization" Macromol. Biosci. 2013, 13, 1389-95 (DOI: 10.1002/mabi.201300203) (published online Jul 16, 2013). 

  67.  C. H. Lee, J. Shin, J. S. Lee, E. Byun, J. H. Ryu, S. H. Um, D.-I. Lee, Haeshin Lee*, S.-W. Cho*, "Bio-inspired, calcium-free alginate hydrogels with tunable physical and mechanical properties and improved biocompatibility" Biomacromolecules 2013, 14, 2004-2013 (DOI: 10.1021/bm400352d) (published online May 2, 2013) 

  68.  K. Kim, J. H. Ryu, D. Y. Lee, Haeshin Lee* "Bio-inspired catechol conjugation converts water-insoluble chitosan into a highly water-soluble, adhesive chitosan derivative for hydrogels and LbL assembly" Biomaterials Sci. 2013, 1, 783-790 (DOI: 10.1039/c3bm00004d) (Published online May 2, 2013). 

  69.  M.-H. Ryou, J. Kim, I. Lee, S. Kim, Y. K. Jeong, S. Hong, J. H. Ryu, T.-S. Kim, J.-Ki Park, Haeshin Lee*, J. W. Choi* "Mussel-inspired adhesive binders for high performance nano- silicon anodes in Li-ion batteries" Adv. Mater. 2013, 25, 1571-76 (Frontpiece Paper) (DOI: 10.1002/adma.201203981) (Pub date: Dec 27th, 2012) 

  70.  J.-H. Jeong, S. Yook, Haeshin Lee, Cheol-Hee Ahn, Dong Yun Lee, Youngro Byun "Effects of surface camouflaged islet transplantation on pathophysiological progression in db/db type 2 diabetic mouse model" Biochem. Biophys. Res. Comm. 2013, 433, 513-518 

  71.  I. You, N. Yun, Haeshin Lee "Surface-tension-confined microfluidics and their applications" ChemPhysChem 2013, 14, 471-481 (cover paper). 

  72.  Sung Min Kang, Haeshin Lee "Surface modification of highly ordered pyrolytic graphite (HOPG) by a mussel-inspired poly(norepinephrine) coating: characterization and cell adhesion test" Bull. Korean Chem. Soc. 2013, 34, 960-62 

  73.  H. Y. Son, J. J. Ryu, Haeshin Lee*, Y. S. Nam* "Silver-polydopamine hybrid coatings of electrospun poly(vinylalcohol) nanofibers" Macromol. Mater. & Eng. 2013, 298, 547-554. 

  74.  S. Hong, K. Yang, B. Kang, C. Lee, I.-T. Song, E. K. Byun, K. I. Park, S.-W Cho, Haeshin Lee "Hyaluronic acid-catechol: a biopolymer exhibiting pH-dependent adhesive or cohesive property for human neural stem cell engineering" Adv. Func. Mater. 2013, 23, 1774-80 (DOI: 10.1002/adfm.201202365) (Nov 7th) (April 12th). 

  75.  C. J. Kastrup, M. Nahredorf, J. L. Figueiredo, Haeshin Lee, S. Kambhampati, T. Lee, S.-W. Cho, R. Gorbatov, T. T. Dang, P. Dutta, R. Weissleder, R. Langer, D. G. Anderson "Painting blood vessels and atherosclerotic plaques with an adhesive drug depot" Proc. Natl. Acad. Sci. USA 2012, 109, 21444-9 (Dec 26th) 

  76.  Y.J. Oh, I. Hwan Cho, Haeshin Lee, K.-J. Park, H. Lee, S. Y. Park "Bio-inspired catechol chemistry: a new way to develop a re-moldable and injectable coacervate hydrogel" Chem. Comm. 2012, 48, 11895-97 (Oct. 24, 201) 

  77.  Il Kim, Seung-Ho Kim, Inseong You, Haeshin Lee, Kyung-Wook Paik "Bio-inspired surface treatment on touch screen panels (TSPs) for adhesion enhancement" Electronic Components & Tech. Conference 2012. 

  78.  M. Lee, J. Rho, D.-E. Lee, S. Hong, S.-J. Choi, P. B. Messersmith, Haeshin Lee "Water detoxification by a substrate-bound catecholamine adsorbent" ChemPlusChem 2012, 77, 987-990 DOI: 10.1002/cplu.201200209 (Sep. 25th) 

  79.  S. M. Kang, M.-H. Ryou, J. W. Choi, Haeshin Lee. "Mussel- and diatom-inspired silica coating on separators yields improved power and safety in Li-ion batteries" Chem. Mater. 2012 24, 3481-3485 (Aug 15th) 

  80.  K. Yang, J. S. Lee, J. Kim, Y. B. Lee, H. Shin, S. H. Um, J. B. Kim, K. I. Park, Haeshin Lee, S.-W. Cho. "Polydopamine-mediated surface modification of scaffold materials for human stem cell engineering" Biomaterials 2012, 33, 6952-6964 DOI:10.1016/j.biomaterials.2012.06.067) (July 17) 

  81.  H.-L Che, I. H. Bae, K.S. Lim, I. T. Song, H. Lee, M. Muthiah, R. Namgung, W. J. Kim, D.-G. Kim, Y. Ahn, M.-H. Jeong, I.-K. Park. "Suppression of post-angioplasty restenosis with an Akt1 siRNA-embedded coronary stent in a rabbit model" Biomaterials, 2012, 33, 8548-8556 (2012. 11 pub date) 

  82.   J. M. Lee, B.-S. Kim, Haeshin Lee, Gun-Il Im "In vivo tracking of mesenchymal stem cells using fluorescent nanoparticles in an osteochondral repair model" Mol. Ther. 2012, 20, 1434-1442 (DOI: 10.1038/mt.2012.60) 

  83.   S. Hong, Y. S. Na, S. Choi, I.-T. Song, W. Y. Kim, Haeshin Lee* "Non-covalent self-assembly and covalent polymerization co-contribute to polydopamine formation" Adv. Func. Mater. 2012, 22, 4711-4717 (DOI: 10.1002/adfm.201201156), (July 5th) 

  84.  E. Kim, I.-T. Song, S. Lee, J.-S. Kim, J.-H. Jang* Haeshin Lee* "Drawing Sticky adeno- associated virus for spatially patterned gene expression" Angew. Chem. Int. Ed. 2012, 51, 5598-5601 (DOI: 10.1002/anie.201201495), (pub date: April 26, 2012) 

  85.  S. M. Kang, N. S. Hwang, J. Yeom, S. Y. Park, P. B. Messersmith, I. S. Choi, R. Langer, D. G. Anderson, Haeshin Lee, "One-step multifunctional surface functionalization by adhesive catecholamine" Adv. Func. Mater. 2012, 22, 2949-2955 (DOI:10.1002/adfm.201200177, July 24) 

  86.  I. You, S. M. Kang, S. Lee, Y. O. Cho, J. B. Kim, S. B. Lee, Y. S. Nam, Haeshin Lee "Polydopamine microfluidic system toward two-dimensional, gravity-driven mixing device" Angew. Chem. Int. Ed. 2012, 51, 6126-6130 DOI: 10.1002/anie.201200329 (pub. Date: May 4th, 2012) 

  87.  I. Bae, I.-K. Park, D.-S Park, Haeshin Lee, M.-H. Jeong "Thromboresistant and endothelialization effect of dopamine-mediated heparin coating on a stent material surface" J. Mater. Sci. Mater. Med. 2012, 23, 1259-1269 

  88.  S. Yook, Y. Jung, S. W. Hong, B.-H. Im, J. W. Seo, J. B. Park, M. Lee, C.-H. Ahn, Haeshin Lee, D. Y. Lee, Y. Byun. "Molecularly engineered islet cell clusters for diabetes mellitus treatment" Cell Transplantation (IF 6.2) 2012, 21, 1775-1789 

  89.  C. A. Hong, S. H. Lee, J. S. Kim, J. W. Park, K. H. Bae, H. Mok, T. G. Park, Haeshin Lee "Gene silencing by siRNA microhydrogels via polymeric nanoscale condensation" J. Am. Chem. Soc. 2011, 133, 13914-13917 (2011.08.11 pub date) 

  90.  B. H. Kim, D. H. Lee, J. Y. Kim, D. O. Shin, H. Y. Jeong, S. Hong, J. M. Yun, C. M. Koo, Haeshin Lee*, S. O. Kim* "Mussel-inspired block copolymer lithography for low surface energy materials of Teflon, graphene, and gold" Adv. Mater. 2011, 23, 5618-5622 (Oct. 21th online published) 

  91. S. Hong, J. S. Lee, J. Ryu, S. H. Lee, D. Y. Lee, D.-P. Kim, C. B. Park, Haeshin Lee "Bio- inspired strategy for on-surface synthesis of silver nanoparticles for metal/organic hybrid nanomaterials and LDI-MS substrates" Nanotechnology 2011, 22, 494020 (December pub.) 

  92.  I. You, S. M. Kang, Y. Byun, Haeshin Lee "Enhancement of blood compatibility of poly(urethane) substrates by mussel-inspired adhesive heparin coating" Bioconj. Chem. 2011, 22, 1264-1269 

  93.  J. H. Ryu, Y. Lee, W. H. Kong, T. G. Kim, T. G. Park, Haeshin Lee "Catechol-functionalized chitosan/pluronic hydrogels for tissue adhesives and hemostatic materials" Biomacromolecules 2011, 12, 2653-2659 

  94.  H. S. Yang, W. G. La, S. H. Bhang, H. J. Kim, G.-I. Im, Haeshin Lee, J. H. Park, B.-S. Kim "Hyaline cartilage regeneration by combined therapy of microfracture and long-termbone morphogenetic protein-2 delivery" Tissue Eng. Part A 2011, 17, 1809-1818 

  95.   S. Hong, K. Y. Kim, J.W. Hwang, S. Y. Park, K. D. Lee, D. Y. Lee, Haeshin Lee "Attenuation of in vivo toxicity of biomaterials by polydopamine surface modification" Nanomedicine 2011, 6, 793-801 (July issue) 

  96.   J-H. Jeong, S. W. Hong, S. Hong, S. Yook, Y. Jung, J-B. Park, C. D. Khue, B-H. Lm, J. Seo, Haeshin Lee, C-H. Ahn, D. Y. Lee, Y. Byun. "Surface camouflage of pancreatic islets using 6- arm-PEG-catechol in combined therapy with tacrolimus and anti-CD154 monoclonal antibody for xenotransplantation" Biomaterials 2011, 32, 7961-7970. 

  97.   J. A. Nam, A. Nahain, S. Hong, K. D. Lee, Haeshin Lee*, S. Y. Park* "Synthesis and characterization of a multi-sensitive crosslinked injectable hydrogel based on pluronic" Macromol. Biosci. 2011, 11, 1594-1601 

  98.   T. S. Shanmugarajan, B.-S. Kim, Haeshin Lee, G.-I. Lim "Growth factors and signaling pathways in the chondrogenic differentiation of mesenchymal stem cells" Tissue Eng. Reg. Med. 2011, 8, 292-299 

  99.   Haeshin Lee*, J. H. Jeong, A.S. Hoffman "Remembering Prof. Tae Gwan Park" Bioconj. Chem. 2011, 22,1257-1258 

  100.  S. Ryu, Y. Lee, J.-W. Hwang, S. Hong, C. Kim, T. G. Park, Haeshin Lee,* S. H. Hong* "High- strength carbon nanotube fibers fabricated by infiltration and curing of mussel-inspired catecholamine polymer" Adv. Mater. 2011, 23, 1971-1975 (March 15, 2011 online). (Cover Article) 

  101.  E. Byun, J. Kim, S. M. Kang, H. Lee, D. Bang, Haeshin Lee " Surface PEGylation via native chemical ligation" Bioconj. Chem. 2011, 22, 4-8 (Jan issue) (Online published on Dec. 3rd, 2010) (DOI: 10.1021/bc100285p) 

  102.  A. Al-Nahain, Haeshin Lee, Y. S. Lee, K. D. Lee, S. Y. Park "Development of disulfide core- crosslinked pluronic nanoparticles as an effective anticancer drug delivery system" Macromol. Biosci. 2011, 11, 1264-1271 

  103.  S. M. Kang, S. Park, D. Kim, R. S. Ruoff, Haeshin Lee " Simultaneous reduction and functionalization of graphene oxide by mussel-inspired chemistry" Adv. Func. Mater. 2011, 21, 108-112 (November 9, 2010 online, doi: 10.1002/adfm201001692) 

  104.  H. O. Ham, Z. Liu, Haeshin Lee, P. B. Messersmith "Facile DNA immobilization of surfaces via catecholamine polymer" Angew. Chem. Int. Ed. 2011, 50, 732-736 

  105.  H. J. Chung*, Haeshin Lee*, K. H. Bae, Y. Lee, J. Park, S. W. Cho, J. Y. Hwang, H. Park, R. Langer, D. Anderson, T. G. Park "A facile synthetic route for surface functionalized magnetic nanoparticles: cell labeling and magnetic resonance imaging studies" ACS Nano 2011, 5, 4329-4336 (co-leading author) 

  106.  S. H. Yang, S. M. Kang, K.-B. Lee, T. D. Chung, Haeshin Lee, I. S. Choi "Mussel-inspired encapsulation and functionalization of individual yeast cells" J. Am. Chem. Soc. 2011, 133, 2795-2797 (Cover Article) 

  107.  T.J. Lee, S.H. Bhang, W.G. La, H.S. Yang, J.Y. Seong, Haeshin Lee, G.I. Im, S.H. Lee, B.S. Kim "Spinner-flask culture induces redifferentiation of de-differentiated chondrocytes" Biotechnol. Letters 2011, 33, 829-836 (Dec 2nd 2010 online) 

  108.  D. J. Siegwart, K. A. Whitehead, L. Nuhn, G. Sahay, H. Cheng, S. Jiang, M. Ma, A. Lytton-Jean, A. Vegas, P. Fenton, C. G. Levin, K. T. Love, Haeshin Lee, C. Cortez, S. P. Collins, Y.F. Li, J. Jang, W. Querbes, C. Zurenko, T. Novobrantseva, R. Langer, D. G. Anderson "Combinatorial- synthesis of chemically diverse core-shell nanoparticles for intracellular delivery" Proc. Natl. Acad. Sci. USA 2011, 108, 12996-13001 

  109.  S. M. Kang, I. You, Woo Kyung Cho, Hyun Kyong Shon, Tae Geol Lee, Insung S. Choi, Jeffrey M. Karp, Haeshin Lee "One-step modification of superhydrophobic surfaces by a mussel- inspired polymer coating" Angew. Chem. Int. Ed. 2010, 49, 9401-9404 (Pub. Date: October 28, 2010) (December 3rd issue) 

  110.  Yuhan Lee, Haeshin Lee, Phillip B. Messersmith, Tae Gwan Park "Bio-inspired polymeric template for 1-D assembly of metallic nanoparticles, semiconductor quantum-dots, and magnetic nanoparticles" Macromol. Rapid Comm. 2010, 31, 2109-2114 (December 15th issue) 

  111.  Haeshin Lee "Intelligent glue" Nature, 2010, 465, 298-299 (pub. date 2010.05.19) 

  112.  Jungki Ryu, Sook Hee Ku, Haeshin Lee*, Chan Beum Park* "Mussel-inspired polydopamine coating as a universal route to hydroxyapatite crystallization" Adv. Func. Mater. 2010, 20, 2132-2139 (Inside Cover Article) 

  113.  Hyukjin Lee, Kang Dae Lee, Kyung Bo Pyo, Sung Young Park, Haeshin Lee "Catechol- grafted poly(ethylene glycol) for PEGylation on versatile substrates" Langmuir, 2010, 26, 3790-3793 

  114.  Yuhan Lee, Hyun Jung Chung, Sangho Yeo, Cheol-Hee Ahn, Haeshin Lee, Phillip B. Messersmith, Tae Gwan Park "Thermo-sensitive, injectable, and tissue adhesive sol-gel transition hyaluronic acid/pluronic hydrogels prepared from bio-inspired catechol-thiol reaction" Soft Matter 2010 6, 977-983 

  115.  S. H. Ku, J. Ryu, S. Hong, Haeshin Lee*, Chan Beum Park* "General functionalization route for cell adhesion on non-wetting surfaces" Biomaterials, 2010, 31, 2535-2541 (March) 

  116.  Sung Min Kang, Junsung Rho, Insung S. Choi, Phillip B. Messersmith, Haeshin Lee "Norepinephrine: Material-independent, multifunctional surface modification reagent" J. Am. Chem. Soc. 2009, 131, 13224-13225 (pug. date: 2009.08.31)     

  117.  Haeshin Lee, Junsung Rho, Phillip B. Messersmith "Facile conjugation of biomolecules onto surfaces via mussel adhesive protein inspired coating" Adv. Mater. 2009, 21, 431-434 

  118.  Y.Lee, Haeshin Lee, T. Hyeon, P. B. Messersmith, T. G. Park "Bio-inspired Surface Immobilization of Hyaluronic Acid on Monodisperse Magnetite Nanocrystals for Targeted Cancer Imaging" Adv. Mater. 2008, 20, 4154-4157. 

  119.  Haeshin Lee, Yuhan Lee, Andrea R. Statz, Junsung Rho, Tae Gwan Park, Phillip B. Messersmith. "Surface-independent Layer-by-Layer Assembly Using Mussel Adhesive Inspired Polymers" Adv. Mater. 2008 20, 1619-1623 

  120.  Haeshin Lee, Shara M. Dellatore, William M. Miller, Phillip B. Messersmith. "Mussel-inspired Surface Chemistry for Multifunctional Coatings" Science 2007, 318, 426-430. [This study was highlighted in Nature Materials, 2008, 7, 8-9 & Materials Today, 2007, 10, 15] (pub date 2007.10.19) 

  121.  Haeshin Lee, B. P. Lee, P. B. Messersmith. "A reversible wet/dry adhesive inspired by mussel and gecko adhesion" Nature 2007, 448, 338-341. (July 19th) (Cover Paper) 

  122.  Haeshin Lee, Norbert F. Scherer, Phillip B. Messersmith. "Single molecule mechanics of mussel adhesion" Proc. Natl. Acad. Sci. USA. 2006, 103, 12999-13003. [This study was highlighted in Nature, 2006, 442, 877 & Science, 2006, 313, 1025] 

  123.   J. M. Zhao, Haeshin Lee, R. Nome, S. Majid, N. F. Scherer, W. D. Hoff. "Single-molecule detection of structural change during PAS domain activation" Proc. Natl. Acad. Sci. USA. 2006, 103, 11561-11566 

  124.  N. D. Catron, Haeshin Lee, P. B. Messersmith. "Enhancement of poly(ethylene glycol) mucoadsorption by biomimetic endgroup functionalization" Biointerphases 2006, 1, 134-141 

  125.  Haeshin Lee, S. H. Choi, T. G. Park. "Direct visualization of hyaluronic acid polymer chain by self-assembled one-dimensional array of gold nanoparticles" Macromolecules 2006, 39, 23-25 

  126.  Haeshin Lee, Tae Gwan Park "A novel method for identifying PEGylation sites using streptavidin and biotin interaction" J. Pharm. Sci. 2003, 92, 97-103 

  127.  Seung Ho Choi, Haeshin Lee, and Tae Gwan Park "PEGylation of G-CSF using cleavable oligo-lactic acid linkage" J. Controlled Rel. 2003, 89, 271-284. 

  128.  Haeshin Lee, Il Ho Chang, Sung Ho Ryo, Tae Gwan Park "N-terminal site-specific mono- PEGylation of Epidermal Growth Factor" Pharm. Res. 2003, 20, 818-825. 

  129.  Haeshin Lee, Tae Gwan Park "Preparation and Characterization of PEGylated Epidermal Growth Factor: Evaluation of In Vitro Biological Activity" Pharm. Res. 2002, 19, 845-851 (Cover Paper). 

  130.  Haeshin Lee, Tae Hyoung Kim, and Tae Gwan Park "Receptor-mediated Gene Delivery System Using Streptavidin and Biotin-derivatized and Pegylated Epidermal Growth Factor" J. Controlled Rel. 2002, 83, 109-119. 

  131.  Haeshin Lee, Ji Hoon Jeong, Tae Gwan Park "PEG grafted polylysine with fusogenic peptide for gene delivery: high transfection efficiency with low cytotoxicity" J. Controlled Rel. 2002, 79, 283-291. 

  132.  Tae Hyoung Kim, Haeshin Lee, Tae Gwan Park "PEGylated Recombinant Human Epidermal Growth Factor for Sustained Release from Biodegradable PLGA Microspheres" Biomaterials 2002, 23, 2311-2317. 

  133.  Haeshin Lee, Ji Hoon Jeong, Tae Gwan Park "A New Gene Delivery Formulation of Polyethylenimine/DNA Complexes Coated with PEG Conjugated Fusogenic Peptide" J. Controlled Rel. 2001, 76, 183-192. 

  134.  Haeshin Lee, J. H. Jeong, J. H. Lee, T. G. Park "Enhancing Transfection Efficiency Using Polyethylene Glycol Grafted Polyethylenimine and Fusogenic Peptide" Biotech. & Bioprocess Eng. 2001, 6, 269-273. 

  135.  J. H. Jeong, S. H. Song, D. W. Lim, Haeshin Lee, T. G. Park "DNA Transfection Using Linear Poly(ethylenimine) Prepared by Controlled Acid Hydrolysis of Poly(2-ethyl-2-oxazoline)" J. Controlled Rel. 2001, 73, 391-399. 

  136.  Haeshin Lee, T. G. Park "Conjugation of Trypsin by Temperature-Sensitive Polymers Containing a Carbohydrate Moiety: Thermal Modulation of Enzyme Activity" Biotechnol. Prog. 1998, 14, 508-516. 

  137.  Haeshin Lee, T. G. Park "Reduction/Oxidation Induced Cleavable/Crosslinkable Temperature- Sensitive Hydrogel Network Containing  

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